HuagongsheHuagongshe Chemistry Print Report · For research reference only
Glycolaldehyde → HCID 69800209, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Glycolaldehyde | HCID 756 | — |
| Reactant | 1-Piperazinecarboxylic acid, ethyl ester | HCID 8431 | — |
| Reactant | HCID 178419129 | HCID 178419129 | — |
| Product | HCID 69800209 | HCID 69800209 | — |
Reaction Steps
Following the procedure described in Petasis N. A. et al. in Tetrahedron (1997), 53, 16463-16470, ethyl-N-piperazine carboxylate was reacted with 3-isopropylphenyl-boron dihydroxide in the presence of glycolaldehyde to provide 4-[2-hydroxy-1-(3-isopropyl-phenyl)-ethyl]-piperazine-1-carboxylic acid ethyl ester (compound 18). The compounds listed in Table III were obtained by the same method.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06916797B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-e5a6f9a438594c738a50f8b83d4cc322 |
| Source note | uspto-grants-2005_07 |