Methanol → Tert-butyl 4-(3-methyl-4-aminophenoxy)piperidine-1-carboxylate

HRID 89558Notes

Reaction equation

HRID 89558 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([CH3:24])[c:18]([N+:21]([O-:22])=[O:23])[cH:19][cH:20]2)[CH2:12][CH2:13]1.[CH3:25][OH:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([O:14][c:15]2[cH:16][c:17]([CH3:24])[c:18]([NH2:21])[cH:19][cH:20]2)[CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 887MethanolHCID 18542679Tert-butyl 4-(3-methyl-4-nitrophenoxy)piperidine-1-carboxylate

Product 1

HCID 18542772Tert-butyl 4-(3-methyl-4-aminophenoxy)piperidine-1-carboxylate

Sources & evidence

ORD record
ord-d7212ae9930643b0ad128e8bc5eb75d6
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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