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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 895845Generated: October 30, 2026

1-(2-Pyrimidinyl)piperazine → HCID 10097652, compound

https://huagongshe.com/reaction/895845

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-(2-Pyrimidinyl)piperazineHCID 88747—
ReactantSodium triacetoxyborohydrideHCID 5049666—
ReactantHCID 11772697HCID 11772697—
ProductHCID 10097652HCID 10097652—

Reaction Steps

(20S)-3β-hydroxy-4,4,20-trimethyl-pregna-8,14-dien-21-al was treated with N-(pyrimidin-2-yl)piperazine and sodium tris(acetoxy)borohydride as described in Example 1h). (20S)-20-[(4-(pyrimidin-2-yl)piperazin-1-yl)methyl]-4,4-dimethyl-5α-pregna-8,14-dien-3β-ol was isolated as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06916921B2
Source datasetuspto-grants-2005_07
ORD IDord-8ca542f370564269b1f8be82729b182c
Source noteuspto-grants-2005_07