HuagongsheHuagongshe Chemistry Print Report · For research reference only
Tetrahydrofuran → HCID 86586577, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Tetrahydrofuran | HCID 8028 | — |
| Reactant | 1-Butanaminium, N,N,N-tributyl-, fluoride, hydrate | HCID 16211673 | — |
| Reactant | HCID 69790268 | HCID 69790268 | — |
| Product | HCID 86586577 | HCID 86586577 | — |
Reaction Steps
2 g pulverized molecular sieve (4 Å) and 1.27 g tetrabutylammoniumfluoride hydrate were added to a solution of 2.0 g (20S)-4,4-dimethyl-20-[((triisopropylsilyl)oxy)methyl]-pregna-5,7-dien-3β-ol in 50 ml tetrahydrofuran were added. The mixture was stirred overnight at room temperature, concentrated under reduced pressure and purified by column chromatography to give 1.17 g of (20S)-4,4,20-trimethyl-pregna-5,7-dien-3β,21-diol benzoate.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06916921B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-93dae63d72b8459aa56333b9abebe768 |
| Source note | uspto-grants-2005_07 |