HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-N-[(1,l-dimethylethoxy)carbonyl]-L-phenylalanine methyl ester → 4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-L-phenylalanine methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-N-[(1,l-dimethylethoxy)carbonyl]-L-phenylalanine methyl ester | HCID 59912888 | — |
| Solvent | Hydrochloric Acid | HCID 313 | — |
| Solvent | 1,4-Dioxane | HCID 31275 | — |
| Product | 4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-L-phenylalanine methyl ester | HCID 59912892 | 87.3% |
Reaction Steps
A solution of 4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-N-[(1,1-dimethylethoxy)carbonyl]-L-phenylalanine methyl ester (210 mg, 0.50 mmol) in 4 N HCl in dioxane (10 mL) was stirred for 1 hr and was concentrated to give 4-(5-chloro-1-methyl-2-oxo-3-pyridinyl)-L-phenylalanine methyl ester (140 mg) as a white powder. LR(+)LSIMS: m/z 641 (2M+H), 321 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06916933B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-129151b9381a40118e2d3cba1121eae7 |
| Source note | uspto-grants-2005_07 |