Pyridine → HCID 57457787, compound

HRID 895998Notes

Reaction equation

HRID 895998 reaction equation
[OH:1][CH2:2][P:3](=[O:10])([O:7][CH2:8][CH3:9])[O:4][CH2:5][CH3:6].[C:11](Cl)(=[O:20])[C:12]1[C:13]([O:18][CH3:19])=[CH:14][CH:15]=[CH:16][CH:17]=1.N1C=CC=CC=1>C(Cl)Cl>[CH3:19][O:18][C:13]1[CH:14]=[CH:15][CH:16]=[CH:17][C:12]=1[C:11]([O:1][CH2:2][P:3]([O:7][CH2:8][CH3:9])([O:4][CH2:5][CH3:6])=[O:10])=[O:20]

Participants

5

Reactant 3

HCID 1049PyridineHCID 76513Diethyl phosphonomethanolHCID 889692-Methoxybenzoyl chloride

Product 1

HCID 57457787HCID 57457787, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

A mixture of diethyl (hydroxymethyl)phosphonate (1.2 mmol), 2-anisoyl chloride (1 mmol) and pyridine (2 mmol) in 5 mL CH2Cl2 were stirred at rt for 4 h. Extraction and chromatography provided diethylphosphonomethyl 2-methoxybenzoate as an oil.

Workup

  1. extractionExtraction and chromatography

Sources & evidence

ORD record
ord-744e3c996ccc45f08ffbc388eab18b31
Source dataset
uspto-grants-2005_07
Patent number
US06919322B2

Reaction notes

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