Bromine → HCID 57457788, compound

HRID 895999Notes

Reaction equation

HRID 895999 reaction equation
[CH3:1][O:2][C:3]1[CH:20]=[CH:19][CH:18]=[CH:17][C:4]=1[C:5]([O:7][CH2:8][P:9]([O:14][CH2:15][CH3:16])([O:11][CH2:12][CH3:13])=[O:10])=[O:6].[Br:21]Br>C(Cl)(Cl)Cl>[Br:21][C:20]1[C:3]([O:2][CH3:1])=[C:4]([CH:17]=[CH:18][CH:19]=1)[C:5]([O:7][CH2:8][P:9]([O:11][CH2:12][CH3:13])([O:14][CH2:15][CH3:16])=[O:10])=[O:6]

Participants

4

Reactant 2

HCID 24408BromineHCID 57457787HCID 57457787, compound

Product 1

HCID 57457788HCID 57457788, compound

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

A mixture of diethylphosphonomethyl 2-methoxybenzoate (1 mmol) and bromine (100 mmol) in 10 mL CHCl3 was stirred at rt for 16 h. Extraction and chromatography provided diethylphosphonomethyl 3-bromo-2-methoxybenzoate as an oil.

Workup

  1. extractionExtraction and chromatography

Sources & evidence

ORD record
ord-a952a3c118f14d45a34a4ed208180cca
Source dataset
uspto-grants-2005_07
Patent number
US06919322B2

Reaction notes

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