Methylamine → HCID 10286505, compound

Participants

Reaction Steps

The butyl (5R)-3-(2,3-dihydro-3-ethyl-2-oxo-6-benzothiazolyl)-2-oxo-5-oxazolidinecarboxylate (EXAMPLE 30, Step 3, 300 mg, 0.823 mmol) is treated with 2N methylamine in MeOH (8.2 mL), and the mixture is stirred at ambient temperature for 1 h. The resulting slurry is diluted with Et2O (10 mL) and filtered to give the title compound, mp 227-229° C.; MS (ESI+) for C14H15N3O4S m/z 322 (M+H)+; [α]25D−43 (c 0.93, DMSO).

Provenance & Evidence