HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-(4-Fluorophenyl)-3-oxo-3-pyridin-4-yl-propionic acid methyl ester → 4-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-2H-isoxazol-5-one
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-(4-Fluorophenyl)-3-oxo-3-pyridin-4-yl-propionic acid methyl ester | HCID 10934615 | — |
| Reactant | 2-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-3-oxo-propionic acid methyl ester | HCID 12991403 | — |
| Product | 4-(4-Fluorophenyl)-3-(2-methylsulfanyl-pyrimidin-4-yl)-2H-isoxazol-5-one | HCID 9836046 | — |
Reaction Steps
Using the procedure from Example 1l set forth above, substitute 2-(4-fluorophenyl)-3-oxo-3-(2-methylsulfanyl-pyrimidin-4-yl)-propionic acid methyl ester for 2-(4-fluorophenyl)-3-oxo-3-pyridin-4-yl-propionic acid methyl ester to produce the title compound.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919346B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-8dbcede163be4125977d8d3c917bce40 |
| Source note | uspto-grants-2005_07 |