HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium hydride → 2-(3-Isopropenyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 1,3-Dihydro-1-(1-methylvinyl)-2H-benzimidazol-2-one | HCID 100278 | — |
| Reactant | 2-(Chloromethyl)-1-isopentyl-benzimidazole-5-carbonitrile | HCID 22349309 | — |
| Reactant | 2-(3-isopropyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile | HCID 22349324 | — |
| Product | 2-(3-Isopropenyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile | HCID 22349287 | — |
Reaction Steps
2-(3-Isopropenyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile was prepared as described for 2-(3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazol-1-ylmethyl)-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile using 2-chloromethyl-1-(3-methyl-butyl)-1H-benzoimidazole-5-carbonitrile and 1-Isopropenyl-1,3-dihydro-benzoimidazol-2-one with NaH as base.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919331B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-5b5fe83fa1fa4bffb7508b4bf63a9654 |
| Source note | uspto-grants-2005_07 |