Urea → HCID 178509535, compound

Participants

Reaction Steps

1H-Benzotriazole-5-carboxylic acid (1.0 g, 6.13 mmol), urea (0.552 g, 9.2 mmol) and sulfamic acid (1.19 g, 12.3 mmol) were heated to 240° C. for 1 h. The solid was triturated with water and the solid refluxed with CH2Cl2 for 1 h and the remaining solid removed by filtration. The solvent was removed to give 1H-benzotriazole-5-carbonitrile 100 mg (14%) as a white solid.

Provenance & Evidence