Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 896422Generated: October 25, 2026

4-(Benzyloxy)piperidine → 6-(4-Benzyloxypiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indole-2-one

https://huagongshe.com/reaction/896422

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Benzyloxy)piperidineHCID 3157460—
Reactant2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acidHCID 22350159—
SolventDiethyl EtherHCID 3283—
Product6-(4-Benzyloxypiperidin-1-carbonyl)-1,5-dihydro-oxazolo[4,5-f]indole-2-oneHCID 22350201—

Reaction Steps

The title compound is prepared from 2-oxo-1,5-dihydro-2H-oxazolo[4,5-f]indole-6-carboxylic acid and 4-benzyloxypiperidine [Tetrahedron 54, 13981, (1998)] according to the method described in Example 1/c. Mp.: 258-261° C. (diethyl ether).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06919355B2
Source datasetuspto-grants-2005_07
ORD IDord-3a28cf19a6924ca684f51b31c4ae099c
Source noteuspto-grants-2005_07