HuagongsheHuagongshe Chemistry Print Report · For research reference only
2(3H)-Benzoxazolone → 4-[2-(2-Oxo-1,3-benzoxazol-3(2H)-yl)ethoxy]benzaldehyde
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2(3H)-Benzoxazolone | HCID 6043 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-(2-Chloroethoxy)benzaldehyde | HCID 143156 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 4-[2-(2-Oxo-1,3-benzoxazol-3(2H)-yl)ethoxy]benzaldehyde | HCID 22351115 | — |
Reaction Steps
Dissolve benzoxazolinone (0.024 mol) in dimethylformamide and add potassium carbonate (0.047 mol). Heat at reflux for 20 minutes and then add the compound obtained in Step A (0.021 mol). Stir magnetically at reflux for 80 minutes. Hydrolyse the reaction mixture in 150 ml of water, suction-filter off the resulting precipitate and recrystallise it from a 5/5 cyclohexane/toluene mixture.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06919362B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-7fe4e1def63840cca8fa5372b59047de |
| Source note | uspto-grants-2005_07 |