Methyl 3-{4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3(2H)-yl)ethoxy]phenyl}-2-propenoate → Methyl 3-{4-[2-(6-benzoyl-2-oxo-1,3-benzothiazol-3(2H)-yl)ethoxy]-phenyl}propanoate

Participants

Reaction Steps

The compound obtained in Example 31 is dissolved in a methanol/dioxane mixture and then a catalytic amount of palladium-on-carbon is added. The reaction is stirred at ambient temperature under a hydrogen atmosphere for from 6 to 15 hours. The carbon is then filtered off and the solvents are removed by evaporation in vacuo. The resulting residue is recrystallised from methanol to yield the title product.

Provenance & Evidence