反应详情

温度

-10 °C

0.1 mol of benzothiazolinone is dissolved in 100 ml of acetic anhydride and the solution is cooled to −10° C. 10 ml of nitric acid are then added dropwise, and the reaction is stirred for 2 hours. The resulting precipitate is filtered off and washed with water, and then purified by chromatography (eluant CH2Cl2 then AcOEt) to yield the title product, which is recrystallised from ethanol.

1. filtrationThe resulting precipitate is filtered off
2. washwashed with water
3. custompurified by chromatography (eluant CH2Cl2