HCID 22351082, compound → HCID 22351140, compound

HRID 896508Notes

Reaction equation

HRID 896508 reaction equation
[S:1]1[CH2:5][CH:4]=[N:3][C:2]1=[O:6].Cl[CH2:8][CH2:9][NH:10][C:11]1[CH:26]=[CH:25][C:14]([CH:15]=[C:16]([C:21]([O:23][CH3:24])=[O:22])[C:17]([O:19][CH3:20])=[O:18])=[CH:13][CH:12]=1>>[O:6]=[C:2]1[N:3]([CH2:8][CH2:9][NH:10][C:11]2[CH:26]=[CH:25][C:14]([CH:15]=[C:16]([C:21]([O:23][CH3:24])=[O:22])[C:17]([O:19][CH3:20])=[O:18])=[CH:13][CH:12]=2)[C:4]2[CH:26]=[CH:11][CH:12]=[CH:13][C:5]=2[S:1]1

Participants

3

Reactant 2

HCID 22351082HCID 22351082, compoundHCID 232058631,3-Thiazol-2(5H)-one

Product 1

HCID 22351140HCID 22351140, compound

Procedure

The procedure is as in Step B of Example 37, starting from thiazolinone and with the replacement of dimethyl 2-{4-[2-chloroethoxy]benzylidene}malonate with dimethyl 2-{4-[(2-chloroethyl)amino]benzylidene}malonate.

Sources & evidence

ORD record
ord-bf76047353634732a9e3b05aee0a40a5
Source dataset
uspto-grants-2005_07
Patent number
US06919362B2

Reaction notes

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