Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 896613Generated: October 30, 2026

Hydrochloric Acid → HCID 22351003, compound

https://huagongshe.com/reaction/896613

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactantt-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)thiazol-3(2H)-yl]propylcarbamateHCID 22351001—
Solvent1,4-DioxaneHCID 31275—
ProductHCID 22351003HCID 22351003122.7%

Reaction Steps

A mixture of t-butyl 3-[4-(4-methoxyphenyl)-2-(phenylimino)thiazol-3(2H)-yl]propylcarbamate (400 mg) and a 4N solution of hydrogen chloride in dioxane (8 ml) was stirred at room temperature for 2 hours. The solvent was evaporated under reduced pressure, and to the residue was added diethyl ether. The insoluble salt was collected by filtration to give the title compound (379 mg) as hydrochloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS06919361B2
Source datasetuspto-grants-2005_07
ORD IDord-61b7b78c8d214e42bf58c67a6f206e31
Source noteuspto-grants-2005_07