Iodine → HCID 86594021, compound

Participants

Reaction Steps

To a solution of 4-bromothiophenol (16 g, 85 mmol) in CH2Cl2 (85 mL) was added iodine (10.7 g, 42 mmol, in CH2Cl2) and triethylamine (11.8 mL, 85 mmol). After 3 h the resulting reaction mixture was diluted with a sodium bisulfite solution and ethyl acetate. The organic extracts were washed (1N NaOH, brine), dried (MgSO4), filtered and concentrated. The resulting residue was stirred vigorously in hexane/ether for 1 h then filtered to afford the 4-bromobenzene disulfide compound as a white powder.

Provenance & Evidence