HCID 10229091, compound → HCID 10187078, compound

Participants

Reaction Conditions

Reaction Steps

To a solution of Example 15 (350 mg, 0.69 mmol) in THF/MeOH/H2O (2:1:1, 15 mL) at 21° C. was added OXONE® (1.1 g, 1.8 mmol). The resulting reaction mixture was stirred 2 h at 21° C. then diluted with a sodium bicarbonate solution and ethyl acetate. The organic extracts were washed (H2O), (brine), dried (MgSO4), filtered and concentrated to afford the title compound as a pale yellow foam.

Provenance & Evidence