HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triphenylphosphine → HCID 22022050, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triphenylphosphine | HCID 11776 | — |
| Reactant | N-Bromosuccinamide | HCID 9834204 | — |
| Reactant | HCID 22022028 | HCID 22022028 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 22022050 | HCID 22022050 | — |
Reaction Steps
A solution of 4-(3-methoxyphenyl)-5-methyl-6-(2-fluorobenzyl)-2-(2-hydroxyethyl)-pyridazin-3-one (from above) and triphenylphospine (570 mg, 22 mmol) in dichloromethane (8 mL) was treated with N-bromosuccinamide (400 mg, 22 mmol) at room temperature for 2 hours. The crude product was used for next step. MS: 431 (MH+).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06921761B2 |
| Source dataset | uspto-grants-2005_07 |
| ORD ID | ord-6de136151fe54057b8274594c636084c |
| Source note | uspto-grants-2005_07 |