Ammonia → 4-{1-(3,4-Dimethyl-benzyl)-piperidin-4-ylamino}-6-ethyl-chromen-2-One

Participants

Role	Name	HCID	Charge
Reactant	Ammonia	HCID 222	—
Reactant	3,4-Dimethylbenzaldehyde	HCID 22278	—
Reactant	6-Ethyl-4-(piperidin-4-ylamino)-chromen-2-one	HCID 22348313	—
Product	4-{1-(3,4-Dimethyl-benzyl)-piperidin-4-ylamino}-6-ethyl-chromen-2-One	HCID 20817740	—

Reaction Steps

Prepared from 6-Ethyl-4-(piperidin-4-ylamino)-chromen-2-one and 3,4-dimethylbenzaldehyde in a manner analogous to that described above. 1H NMR (300 MHz, DMSO-D6) δ ppm 1.21 (m, 3H) 1.77 (m, 2H) 2.16 (m, 2H) 2.27 (m, 6H) 2.66 (m, 2H) 3.07 (m, 2H) 3.45 (m, 2H) 3.73 (m, 1H) 4.23 (m, 2H) 5.36 (m, 1H) 7.25 (m, 5H) 7.44 (m, 1H) 7.95 (m, 1H); MS (DCI/NH3) m/z 391 [M+H]+.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US06921821B2
Source dataset	uspto-grants-2005_07
ORD ID	ord-69fbf1533b5d413088a0be545875876e
Source note	uspto-grants-2005_07