4-Formylbenzoic acid → HCID 87956700, compound

Participants

Reaction Steps

According to Procedure C above, (I) (0.300 g of hydrochloride salt; 1.09 mmol) and 4-formyl-benzoic acid were allowed to react to afford after HPLC purification and precipitation with hydrochloric acid as described before, 0.182 g (35.4%) of the title compound. MS (DCI/NH3)(+)Q1MS m/z 409 (M+H)+; 1H NMR (500 MHz, pyridine-d5) δ ppm 1.78 (m, 2H), 2.13 (m, 4H), 2.89 (m, 2H), 3.42 (s, 3H), 3.56 (m, 1H), 3.57 (s, 2H), 5.72 (s, 1H), 7.15 (dd, J=9.05, 2.81 Hz, 1H), 7.34 (d, J=9.05 Hz, 1H), 7.53 (d, J=8.11 Hz, 2H), 7.62 (br d, J=7.18 Hz, N H), 7.70 (d, J=2.50 Hz, 1H) 8.41 (d, J=8.11 Hz, 2H).

Provenance & Evidence