HCID 10173378, compound → HCID 22346610, compound
Reaction equation
[Cl:1][C:2]1[CH:7]=[C:6]([C:8]2[N:13]=[C:12](Cl)[C:11]([C:15]3[CH:20]=[CH:19][CH:18]=[C:17]([CH3:21])[CH:16]=3)=[C:10]([C:22]3[CH:27]=[CH:26][N:25]=[C:24]([Cl:28])[CH:23]=3)[N:9]=2)[CH:5]=[CH:4][N:3]=1.FC1C=CC(C2C3N([CH:58]=[N:59][N:60]=3)C(NC(C3C=CC=CC=3)(C)C)=NC=2C2C=CN=CC=2)=CC=1>>[CH3:21][C:17]1[CH:16]=[C:15]([C:11]2[C:12]3[N:13]([CH:58]=[N:59][N:60]=3)[C:8]([C:6]3[CH:5]=[CH:4][N:3]=[C:2]([Cl:1])[CH:7]=3)=[N:9][C:10]=2[C:22]2[CH:27]=[CH:26][N:25]=[C:24]([Cl:28])[CH:23]=2)[CH:20]=[CH:19][CH:18]=1Participants
3
Procedure
The title compound was synthesized from 2,6-bis(2-chloro(4-pyridyl))-4-chloro-5-(3-methylphenyl)pyrimidine in the same manner as 2-(8-(4-fluorophenyl)-7-(4-pyridyl)-1,2,4-triazolo[4,3-c]pyrimidin-5-yl)amino-2-phenylpropane; MS (m/z) 434.9 (M+H)+; C22H14Cl2N6 requir. 433.29.
Sources & evidence
- ORD record
- ord-e63fbfd0bf5142eb83c537a0a38ac9c7
- Source dataset
- uspto-grants-2005_07
- Patent number
- US06921762B2
Reaction notes
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