HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → N'-hydroxynonanimidamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Nonanenitrile | HCID 16715 | — |
| Reactant | Hydroxyamine hydrochloride | HCID 443297 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N'-hydroxynonanimidamide | HCID 5074022 | 27% |
Reaction Steps
Octyl cyanide (2 g, 14 mmol) and hydroxylamine hydrochloride (2.495 g, 36 mmol) were dissolved in EtOH (10 mL) and treated with triethylamine (5 mL, 36 mmol) at reflux over night. Extraction: AcOEt/water. Silica gel chromatography: heptane/AcOEt 1:2 afforded a white solid (0.65 g, 26%). MS: m/z=173 (M +H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351700B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-344e2ede1a55402092f36b2c52f6ed11 |
| Source note | uspto-grants-2008_04 |