HRID898223

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC[C@@H]1C(=O)N(C)c2cc(F)ccc2N1C(=O)c1ccc(O)cc1

HCID11709655

未命名化合物

结构：CC[C@H]1C(=O)N(CC)c2ccc(F)cc2N1C(=O)c1ccc(OC)cc1

HCID69222645

未命名化合物

PRODUCTS

生成物

结构：CC[C@H]1C(=O)N(CC)c2ccc(F)cc2N1C(=O)c1ccc(O)cc1

HCID11515674

未命名化合物

收率 93%

PROCEDURE

实验过程

(3S)-1,3-Diethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one was treated according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4-(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (see Example 1) to yield (3S)-1,3-diethyl-6-fluoro-4-(4-hydroxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (93%). [α]D25=+295° (c=0.0098 G/ML, CHCl3); MS (ESI) m/z 343 ([M+H]+); MS (ESI) m/z 341 ([M−H]−); HRMS: calcd for C19H19FN2O3, 342.1380; found (ESI_FT), 343.14475.