HRID898225

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC[C@@H]1C(=O)N(C)c2cc(F)ccc2N1C(=O)c1ccc(O)cc1

HCID11709655

未命名化合物

结构：CC[C@H]1C(=O)N(C)c2ccc(F)cc2N1C(=O)c1ccc(OC)cc1

HCID69222760

未命名化合物

PRODUCTS

生成物

结构：CC[C@H]1C(=O)N(C)c2ccc(F)cc2N1C(=O)c1ccc(O)cc1

HCID11659909

未命名化合物

收率 87%

PROCEDURE

实验过程

(3S)-3-Ethyl-6-fluoro-4-(4-methoxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one was treated according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4-(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (see Example 1) to yield (3S)-3-Ethyl-6-fluoro-4-(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (87%). [α]D25=+301° (c=0.0107 G/ML, CHCl3); MS (ESI) m/z 329 ([M+H]+); MS (ESI) m/z 327 ([M−H]−); HRMS: calcd for C18H17FN2O3, 328.1223; found (ESI_FT), 329.12904;