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HRID898228

反应详情

EQUATION

反应方程式

HRID 898228 的结构方程式

REACTANTS

反应物

2
结构：CC[C@H]1Nc2cc(F)ccc2NC1=O
HCID69222176

未命名化合物

结构：CC[C@@H]1C(=O)Nc2cc(F)ccc2N1C(=O)c1ccc(OC)cc1
HCID69224280

未命名化合物

PRODUCTS

生成物

1
结构：CC[C@@H]1C(=O)Nc2ccc(F)cc2N1C(=O)c1ccc(OC)cc1
HCID69223657

未命名化合物

收率 76%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CCOCC
溶剂HCID3283

Diethyl Ether

C4H10O

PROCEDURE

实验过程

(3R)-3-Ethyl-6-fluoro-3,4-dihydroquinoxalin-2(1H)-one in ether was treated according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (see Example 1) to yield (3R)-3-ethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (76%). MS (ESI) m/z 329 ([M+H]+); MS (ESI) m/z 327 ([M−H]−); HRMS: calcd for C18H17FN2O3, 328.12238; found (ESI_FT), 329.12878.