HRID898233

反应详情

EQUATION

反应方程式

REACTANTS

反应物

结构：CC[C@@H]1C(=O)N(C)c2cc(F)ccc2N1C(=O)c1ccc(O)cc1

HCID11709655

未命名化合物

结构：C=CCN1C(=O)[C@@H](CC)N(C(=O)c2ccc(OC)cc2)c2cc(F)ccc21

HCID69222655

未命名化合物

PRODUCTS

生成物

结构：C=CCN1C(=O)[C@@H](CC)N(C(=O)c2ccc(O)cc2)c2cc(F)ccc21

HCID11566547

未命名化合物

收率 97%

PROCEDURE

实验过程

(3R)-1-Allyl-3-ethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (see Example 9) was treated according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4-(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (see Example 1) to yield (3R)-1-allyl-3-ethyl-6-fluoro-4-(4-hydroxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (97%). [α]D25=−285° (c=0.0102 G/ML, CHCl3); MS (ESI) m/z 355 ([M+H]+); MS (ESI) m/z 353 ([M−H]−); HRMS: calcd for C20H19FN2O3, 354.1380; found (ESI_FT), 355.1449.