(3R)-3-ethyl-7-fluoro-4-(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one → HCID 11567129, compound

Participants

Reaction Steps

(3R)-1-Cyclopentyl-3-ethyl-6-fluoro-4-(4-methoxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one was treated according to the procedure for the preparation of (3R)-3-ethyl-7-fluoro-4(4-hydroxybenzoyl)-1-methyl-3,4-dihydroquinoxalin-2(1H)-one (see Example 1) to yield (3R)-1-cyclopentyl-3-ethyl-6-fluoro-4-(4-hydroxybenzoyl)-3,4-dihydroquinoxalin-2(1H)-one (40%). [α]D25=−309° (c=0.0095 G/ML, CHCl3); MS (ESI) m/z 383 ([M+H]+); MS (ESI) m/z 381 ([M−H]−); HRMS: calcd for C22H23FN2O3, 382.1693; found (ESI_FT), 383.17555.

Provenance & Evidence