HuagongsheHuagongshe Chemistry Print Report · For research reference only
2,5-Difluoronitrobenzene → (2S)-2-[(4-fluoro-2-nitrophenyl)amino]butanoic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2,5-Difluoronitrobenzene | HCID 67767 | — |
| Reactant | (-)-2-Aminobutyric acid | HCID 80283 | — |
| Reactant | (R)-2-(4-fluoro-2-nitrophenylamino)-butyric acid | HCID 69223325 | — |
| Product | (2S)-2-[(4-fluoro-2-nitrophenyl)amino]butanoic acid | HCID 69222707 | — |
Reaction Steps
2,5-Difluoronitrobenzene was treated with (S)-2-aminobutyric acid according to the procedure for the preparation of (R)-2-(4-fluoro-2-nitrophenylamino)-butyric acid (see Example 1) to yield (2S)-2-[(4-fluoro-2-nitrophenyl)amino]butanoic acid. MS (ESI) m/z 243 ([M+H]+); MS (ESI) m/z 241 ([M−H]−).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351709B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-419b62b4a0d946f1ab0214fc8f790c09 |
| Source note | uspto-grants-2008_04 |