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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898274Generated: October 25, 2026

(-)-2-Aminobutyric acid → (2S)-2-[(5-bromo-2-nitrophenyl)amino]butanoic acid

https://huagongshe.com/reaction/898274

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(-)-2-Aminobutyric acidHCID 80283—
Reactant4-Bromo-2-fluoro-1-nitrobenzeneHCID 2783362—
Reactant(R)-2-(4-fluoro-2-nitrophenylamino)-butyric acidHCID 69223325—
Product(2S)-2-[(5-bromo-2-nitrophenyl)amino]butanoic acidHCID 69223544—

Reaction Steps

4-Bromo-2-fluoronitrobenzene was treated with (S)-2-aminobutyric acid according to the procedure for the preparation of (R)-2-(4-fluoro-2-nitrophenylamino)-butyric acid (see Example 1) to yield (2S)-2-[(5-bromo-2-nitrophenyl)amino]butanoic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351709B2
Source datasetuspto-grants-2008_04
ORD IDord-cb2d6b71ee1645b096f83602f5fb7818
Source noteuspto-grants-2008_04