Fluorene-1-carbonyl chloride → HCID 69305054, compound

HRID 898511Notes

Reaction equation

HRID 898511 reaction equation
[CH3:1][CH:2]([CH:8]([OH:10])[CH3:9])[C:3]([O:5][CH2:6][CH3:7])=[O:4].[C:11]1([C:24](Cl)=[O:25])[C:23]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]=2[CH:14]=[CH:13][CH:12]=1>>[CH3:1][CH:2]([CH:8]([O:10][C:24]([C:11]1[C:23]2[CH2:22][C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[C:15]=2[CH:14]=[CH:13][CH:12]=1)=[O:25])[CH3:9])[C:3]([O:5][CH2:6][CH3:7])=[O:4]

Participants

3

Reactant 2

HCID 255028Fluorene-1-carbonyl chlorideHCID 656467Ethyl 3-hydroxy-2-methylbutyrate

Product 1

HCID 69305054HCID 69305054, compoundYield 25%

Procedure

0.01 Mole of ethyl 2-methyl-3-fluorenoyloxybutyrate was prepared from 0.04 mol of ethyl 2-methyl-3-hydroxybutyrate and 0.05 mol of fluorenoyl chloride (9-fluorenyl carbonyl chloride) following the procedure as described in step 3) of the Preparation Example 3. Yield 25%.

Workup

  1. customof the Preparation Example 3

Sources & evidence

ORD record
ord-04fd5a6b8a08430db3645c53572b0d86
Source dataset
uspto-grants-2008_04
Patent number
US07351778B2

Reaction notes

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