反应详情

84 mL of 2 M aqueous NaOH was added to a solution of 23.97 g (0.084 mol) of ethyl (2-chloro-4-trifluoromethyl-phenoxy)-acetate in 200 mL EtOH and the mixture was refluxed for 1 hour. EtOH was concentrated by evaporation i. vac., the residue was diluted with ice water and acidified with 2 M aqueous HCl. The precipitate formed was filtered off, washed with water and dried at 70° C. i. vac.

1. temperaturethe mixture was refluxed for 1 hour
2. concentrationEtOH was concentrated by evaporation i
3. addition, the residue was diluted with ice water
4. customThe precipitate formed
5. filtrationwas filtered off
6. washwashed with water
7. customdried at 70° C. i