HuagongsheHuagongshe Chemistry Print Report · For research reference only
Diethyl[2-(2-methyl-4-nitrophenoxy)ethyl]amine → N-[2-(4-Amino-2-methylphenoxy)ethyl]-N,N-diethylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Diethyl[2-(2-methyl-4-nitrophenoxy)ethyl]amine | HCID 68816853 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | N-[2-(4-Amino-2-methylphenoxy)ethyl]-N,N-diethylamine | HCID 26189998 | — |
Reaction Steps
3.10 g (12.3 mmol) diethyl-[2-(2-methyl-4-nitro-phenoxy)-ethyl]-amine were dissolved in 250 mL ethyl acetate, 0.55 g Raney nickel was added and the mixture was hydrogenated for 36 hours at 50 psi and ambient temperature. The catalyst was filtered off and the filtrate evaporated down i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-07769d93a6aa47128b8a0fcf961dd42b |
| Source note | uspto-grants-2008_04 |