HCID 68875673, compound → HCID 59691647, compound

HRID 898548Notes

Reaction equation

HRID 898548 reaction equation
[C:1]([O:5][C:6]([N:8]([CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([N+:19]([O-])=O)=[CH:15][C:14]=1[Cl:22])[CH3:9])=[O:7])([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6]([N:8]([CH3:9])[CH2:10][CH2:11][O:12][C:13]1[CH:18]=[CH:17][C:16]([NH2:19])=[CH:15][C:14]=1[Cl:22])=[O:7])([CH3:4])([CH3:3])[CH3:2]

Participants

3

Reactant 1

HCID 68875673HCID 68875673, compound

Product 1

HCID 59691647HCID 59691647, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The product was obtained analogously to Intermediate product 29b starting from 4.19 g (12.7 mmol) N-tert.butoxycarbonyl-N-methyl-[2-(2-chloro-4-nitro-phenoxy)-ethyl]-amine by hydrogenation with 500 mg Raney nickel at 3 bar.

Sources & evidence

ORD record
ord-fbbe81dfd3144734bc0b1246c8c3c462
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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