HCID 68877962, compound → HCID 59691590, compound

HRID 898549Notes

Reaction equation

HRID 898549 reaction equation
[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([N+:18]([O-])=O)=[CH:14][C:13]=1[Cl:21])=[O:7])([CH3:4])([CH3:3])[CH3:2]>[Ni]>[C:1]([O:5][C:6]([NH:8][CH2:9][CH2:10][O:11][C:12]1[CH:17]=[CH:16][C:15]([NH2:18])=[CH:14][C:13]=1[Cl:21])=[O:7])([CH3:4])([CH3:2])[CH3:3]

Participants

3

Reactant 1

HCID 68877962HCID 68877962, compound

Product 1

HCID 59691590HCID 59691590, compound

Reagents, catalysts & solvents 1

HCID 935NickelCatalyst

Procedure

The product was obtained analogously to Intermediate product 29b starting from 2.25 g (7.10 mmol) N-tert.butoxycarbonyl-[2-(2-chloro-4-nitro-phenoxy)-ethyl]-amine by hydrogenation with 500 mg Raney nickel at 3 bar.

Sources & evidence

ORD record
ord-0e5dee5c116b4858a1b729129ac2f307
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

Loading…