HuagongsheHuagongshe Chemistry Print Report · For research reference only
[2-(2-Chloro-4-nitrophenyl)ethyl]diethylamine → 3-Chloro-4-(2-diethylaminoethyl)phenylamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | [2-(2-Chloro-4-nitrophenyl)ethyl]diethylamine | HCID 68816908 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-Chloro-4-(2-diethylaminoethyl)phenylamine | HCID 59691617 | — |
Reaction Steps
A suspension of 2.00 g (7.790 mmol) [2-(2-chloro-4-nitro-phenyl)-ethyl]-diethyl-amine and 0.80 g Raney nickel in THF was hydrogenated for 2.5 h at RT and 25 psi hydrogen pressure. The catalyst was filtered off and the filtrate evaporated down i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-53c17b045afb46c680947db18f8e2a89 |
| Source note | uspto-grants-2008_04 |