HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-ol → 3-(2-Chloro-4-nitro-phenyl)-propan-1-ol
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-(2-Chloro-4-nitro-phenyl)-prop-2-yn-1-ol | HCID 23006416 | — |
| Reactant | HCID 178418361 | HCID 178418361 | — |
| Catalyst | Nickel | HCID 935 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | 3-(2-Chloro-4-nitro-phenyl)-propan-1-ol | HCID 68877970 | — |
Reaction Steps
A suspension of 1.25 g (6.808 mmol) 3-(2-chloro-4-nitro-phenyl)-prop-2-yn-1-ol and 1.00 g Raney nickel in 50 mL THF was hydrogenated for 12 h at RT and 25 psi hydrogen pressure. The catalyst was filtered off and the filtrate was evaporated down i. vac.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-09c178bafa9f4658a483d396244039d4 |
| Source note | uspto-grants-2008_04 |