N-Ethylaniline → n-{3-Chloro-4-[2-(ethyl-phenyl-amino)-ethoxy]-phenyl}-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

HRID 898571Notes

Reaction equation

HRID 898571 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([NH:12][C:13](=[O:27])[CH2:14][O:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:25])([F:24])[F:23])=[CH:18][C:17]=2[Cl:26])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH:10]=O.[CH2:28]([NH:30][C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1)[CH3:29]>>[Cl:1][C:2]1[CH:3]=[C:4]([NH:12][C:13](=[O:27])[CH2:14][O:15][C:16]2[CH:21]=[CH:20][C:19]([C:22]([F:23])([F:24])[F:25])=[CH:18][C:17]=2[Cl:26])[CH:5]=[CH:6][C:7]=1[O:8][CH2:9][CH2:10][N:30]([CH2:28][CH3:29])[C:31]1[CH:36]=[CH:35][CH:34]=[CH:33][CH:32]=1

Participants

3

Reactant 2

HCID 7670N-EthylanilineHCID 59691552n-[3-Chloro-4-(2-oxo-ethoxy)-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

Product 1

HCID 59691689n-{3-Chloro-4-[2-(ethyl-phenyl-amino)-ethoxy]-phenyl}-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

Procedure

The product was obtained according to general working method V starting from 0.422 g (0.616 mmol) N-[3-chloro-4-(2-oxo-ethoxy)-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide (Z3d) and 0.094 mL (0.739 mmol) N-ethylaniline.

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-0897e8022e76404d954f29a65fbe8c8e
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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