(2-Chloro-4-trifluoromethyl-phenoxy)-acetic acid → Ethyl 2-[2-(2-chloro-4-trifluoromethyl-phenoxy)-acetylamino]-5-(2-diethylamino-ethoxy)-benzoate

HRID 898572Notes

Reaction equation

HRID 898572 reaction equation
[Cl:1][C:2]1[CH:12]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([OH:8])=O.[NH2:17][C:18]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][CH2:31][N:32]([CH2:35][CH3:36])[CH2:33][CH3:34])=[CH:25][C:19]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21]>>[Cl:1][C:2]1[CH:12]=[C:11]([C:13]([F:16])([F:15])[F:14])[CH:10]=[CH:9][C:3]=1[O:4][CH2:5][C:6]([NH:17][C:18]1[CH:28]=[CH:27][C:26]([O:29][CH2:30][CH2:31][N:32]([CH2:35][CH3:36])[CH2:33][CH3:34])=[CH:25][C:19]=1[C:20]([O:22][CH2:23][CH3:24])=[O:21])=[O:8]

Participants

3

Reactant 2

HCID 59691547(2-Chloro-4-trifluoromethyl-phenoxy)-acetic acidHCID 59691685Ethyl 2-amino-5-(2-diethylamino-ethoxy)-benzoate

Product 1

HCID 59691585Ethyl 2-[2-(2-chloro-4-trifluoromethyl-phenoxy)-acetylamino]-5-(2-diethylamino-ethoxy)-benzoate

Procedure

The product was obtained according to general working method I starting from 1.00 g (3.567 mmol) (2-chloro-4-trifluoromethyl-phenoxy)-acetic acid (Z2b) and 0.908 g (3.567 mmol) ethyl 2-amino-5-(2-diethylamino-ethoxy)-benzoate (Z25c).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-cb7593481d7f46fb885a118e5622bc9f
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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