HuagongsheHuagongshe Chemistry Print Report · For research reference only
N,N,N'-trimethyl-N'-(4-nitrophenyl)-1,2-ethanediamine → N-(2-Dimethylaminoethyl)-N-methylbenzene-1,4-diamine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | N,N,N'-trimethyl-N'-(4-nitrophenyl)-1,2-ethanediamine | HCID 21873305 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | N-(2-Dimethylaminoethyl)-N-methylbenzene-1,4-diamine | HCID 21873395 | — |
Reaction Steps
A suspension of 5.770 g (25.842 mmol), N,N′-trimethyl-N′-(4-nitro-phenyl)-ethane-1,2-diamine (141a) and 0.60 g Pd/C (10%) in EtOH was hydrogenated for 4.5 h at 50 psi. The catalyst was filtered off and the filtrate evaporated down i. vac. The crude product was further reacted immediately.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351719B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-7878492f0f3a4ecaa27b3ed7d9172791 |
| Source note | uspto-grants-2008_04 |