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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898602Generated: October 26, 2026

4-Methoxypiperidine → n-{3-Chloro-4-[2-(4-methoxy-piperidin-1-yl)-ethoxy]-phenyl}-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide

https://huagongshe.com/reaction/898602

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethoxypiperidineHCID 77666—
ReactantN-[4-(2-bromo-ethoxy)-3-chloro-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamideHCID 59691643—
Productn-{3-Chloro-4-[2-(4-methoxy-piperidin-1-yl)-ethoxy]-phenyl}-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamideHCID 10481816—

Reaction Steps

Prepared analogously to Example 145 starting from N-[4-(2-bromo-ethoxy)-3-chloro-phenyl]-2-(2-chloro-4-trifluoromethyl-phenoxy)-acetamide (Z28b) and 4-methoxy-piperidine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351719B2
Source datasetuspto-grants-2008_04
ORD IDord-0b9aaa0aae154160ba711f99f98c5255
Source noteuspto-grants-2008_04