3-Chloro-4-(2-diethylaminoethoxy)phenylamine → 2-(2-bromo-4-trifluoromethyl-phenylamino)-N-[3-chloro-4-(2-diethylamino-ethoxy)-phenyl]-acetamide

HRID 898613Notes

Reaction equation

HRID 898613 reaction equation
[Br:1][C:2]1[CH:7]=[C:6]([C:8]([F:11])([F:10])[F:9])[CH:5]=[CH:4][C:3]=1[NH:12][CH2:13][C:14]([OH:16])=O.[Cl:17][C:18]1[CH:19]=[C:20]([NH2:32])[CH:21]=[CH:22][C:23]=1[O:24][CH2:25][CH2:26][N:27]([CH2:30][CH3:31])[CH2:28][CH3:29]>>[Br:1][C:2]1[CH:7]=[C:6]([C:8]([F:9])([F:10])[F:11])[CH:5]=[CH:4][C:3]=1[NH:12][CH2:13][C:14]([NH:32][C:20]1[CH:21]=[CH:22][C:23]([O:24][CH2:25][CH2:26][N:27]([CH2:30][CH3:31])[CH2:28][CH3:29])=[C:18]([Cl:17])[CH:19]=1)=[O:16]

Participants

3

Reactant 2

HCID 167916763-Chloro-4-(2-diethylaminoethoxy)phenylamineHCID 68878331(2-Bromo-4-trifluoromethyl-phenylamino)-acetic acid

Product 1

HCID 100754562-(2-bromo-4-trifluoromethyl-phenylamino)-N-[3-chloro-4-(2-diethylamino-ethoxy)-phenyl]-acetamide

Procedure

The product was obtained according to general working method I starting from (2-bromo-4-trifluoromethyl-phenylamino)-acetic acid (Example 167b) and 3-chloro-4-(2-diethylamino-ethoxy)-phenylamine (Z1b).

Workup

  1. customThe product was obtained

Sources & evidence

ORD record
ord-5be1785fbfd74363b6132ec03ecce67e
Source dataset
uspto-grants-2008_04
Patent number
US07351719B2

Reaction notes

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