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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 898622Generated: October 31, 2026

(E)-3-(4'-chlorobiphenyl-4-yl)acrylic Acid → (e)-3-(4'-Chloro-biphenyl-4-yl)-n-methyl-n-(4-piperidin-1-ylmethyl-phenyl)-acrylamide

https://huagongshe.com/reaction/898622

Reaction equation

Participants

RoleNameHCIDCharge
Reactant(E)-3-(4'-chlorobiphenyl-4-yl)acrylic AcidHCID 5957595—
ReactantMethyl-(4-piperidin-1-ylmethyl-phenyl)-amineHCID 18319987—
Product(e)-3-(4'-Chloro-biphenyl-4-yl)-n-methyl-n-(4-piperidin-1-ylmethyl-phenyl)-acrylamideHCID 59691584—

Reaction Steps

Prepared analogously to Example 172 starting from (E)-3-(4′-chloro-biphenyl-4-yl)-acrylic acid and methyl-(4-piperidin-1-ylmethyl-phenyl)-amine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07351719B2
Source datasetuspto-grants-2008_04
ORD IDord-56a8617660344e4d91c3831e0b4a0ad6
Source noteuspto-grants-2008_04