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HRID898742

反应详情

EQUATION

反应方程式

HRID 898742 的结构方程式

REACTANTS

反应物

2
结构：O
HCID962

Water

H2O

结构：CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC
HCID441313

Perindopril erbumine

C23H43N3O5

PRODUCTS

生成物

1
结构：CC(C)(C)N.CCC[C@H](N[C@@H](C)C(=O)N1[C@H](C(=O)O)C[C@@H]2CCCC[C@@H]21)C(=O)OCC.O
HCID9847044

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：CC#N
溶剂HCID6342

Acetonitrile

C2H3N

PROCEDURE

实验过程

Perindopril erbumine (5 gms) was suspended in acetonitrile (75 ml). To this was added water (0.4 ml) and the contents heated to dissolve the solids and cooled to 0 EC. The resulting slurry was filtered to obtain perindopril erbumine monohydrate (2.9 gms).

WORKUP

后处理

  1. temperaturethe contents heated
  2. dissolutionto dissolve the solids
  3. temperaturecooled to 0 EC
  4. filtrationThe resulting slurry was filtered