HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Fluoro-p-anisaldehyde → N-tert-Butyl-4-((3-fluoro-4-methoxybenzylidene)amino)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Fluoro-p-anisaldehyde | HCID 67696 | — |
| Reactant | 4-Amino-N-(1,1-dimethylethyl)benzenesulfonamide | HCID 832627 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-tert-Butyl-4-((3-fluoro-4-methoxybenzylidene)amino)benzenesulfonamide | HCID 11132250 | 99.6% |
Reaction Steps
A mixture of 4-amino-N-tert-butylbenzenesulfonamide (52.3 g, 0.23 mol, obtained in example 1), 3-fluoro-4-methoxybenzaldehyde (35.3 g, 0.23 mol) and toluene (2.5 L) is heated at reflux in a Dean-Stark for 24 h. The solvent is removed, yielding 83.5 g of the title compound (yield: quantitative).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351836B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-f994231939c84ac8abfc9d6de871a64e |
| Source note | uspto-grants-2008_04 |