HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → (4-{2-[2-(Methoxycarbonyl)phenoxy]ethyl}phenoxy)acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | Methyl 2-{2-[4-(2-tert-butoxy-2-oxoethoxy)phenyl]ethoxy}benzoate | HCID 69259306 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | (4-{2-[2-(Methoxycarbonyl)phenoxy]ethyl}phenoxy)acetic acid | HCID 69258392 | 95% |
Reaction Steps
Methyl 2-{2-[4-(2-tert-butoxy-2-oxoethoxy)phenyl]ethoxy}benzoate (0.400 g, 1.0351 mmol) was dissolved in DCM and trifluoracetic acid (0.8 ml, 8.281 mmol) was added. The mixture was stirred at room temperature for 3 h. The solvent was evaporated to give 325 mg of a white powder.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07351858B2 |
| Source dataset | uspto-grants-2008_04 |
| ORD ID | ord-03c3e0039056428a82fe06c4ce0e4358 |
| Source note | uspto-grants-2008_04 |