Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 899083Generated: October 28, 2026

2-(Trifluoromethoxy)benzyl bromide → 1-(4-Benzyl-morpholin-2-yl)-1-phenyl-2-(2-trifluoromethoxy-phenyl)-ethanol

https://huagongshe.com/reaction/899083

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-(Trifluoromethoxy)benzyl bromideHCID 2777254—
ReactantHCID 69289142HCID 69289142—
Product1-(4-Benzyl-morpholin-2-yl)-1-phenyl-2-(2-trifluoromethoxy-phenyl)-ethanolHCID 69292293—

Reaction Steps

The procedure for the synthesis of example 1a, 1-(4-Benzyl-morpholin-2-yl)-2-(2-methoxy-phenyl)-1-phenyl-ethanol, was followed using 2-(trifluoromethoxy)benzyl bromide (available from Fluorochem) as starting material and making non-critical variations, to yield the title compound. FIA [M+H]+=458.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07354920B2
Source datasetuspto-grants-2008_04
ORD IDord-042cb15b887c4259a82bb98e2e3a3a98
Source noteuspto-grants-2008_04