Benzylethanolamine → HCID 86086575, compound

Participants

Reaction Steps

Benzenesulfonyl chloride (2.2 ml, 0.0175 mol) was added dropwise at 0° C. to a well-stirred solution of N-benzyl ethanolamine (1 g, 0.7 mmol) and triethylamine (2.4 ml. 0.0175 mol) in dry dichloromethane (10 ml). The reaction mixture was stirred at room temperature for 1 h and quenched with water. The compound was extracted with dichloromethane, organic layer was washed with water, brine and dried over sodium sulfate. Solvent evaporation under reduced pressure afforded 0.6 g of the desired product as a solid. This was directly taken for next step without further purification.

Provenance & Evidence