(3-Chlorophenyl)boronic acid → HCID 135399711, compound

Participants

Reaction Steps

This compound was prepared from 7-bromo-3,9-dihydroxy-6H-chromeno[4,3-b]quinoline (7) using 3-chlorophenylboronic acid according to method M. Orange powder; Yield: 94%; mp 162-165° C. (dec.); 1H-NMR (400 MHz, DMSOd-6) δ 5.01 (s, 2H), 6.36 (d, J=2.3 Hz, 1H), 6.60 (dd, J=8.5, 2.2 Hz, 1H), 6.61 (d, J=2.6 Hz, 1H), 7.26 (dd, J=9.1, 2.6 Hz, 1H), 7.35 (m, 1H), 7.50 (d, J=1.0 Hz, 1H), 7.64 (dd, J=3.9, 1.6, Hz, 2H), 7.90 (d, J=9.1 Hz, 1H), 8.15 (d, J=8.8 Hz, 1H), 9.86 (s, 1H), 9.98 (s, 1H); MS (ESI) m/z 374/376 ([M−H]−), 376/378 ([M+H]+); HRMS (ESI+) calcd for C22H14ClNO3 376.0735 ([M+H]+). Found: 376.0721.

Provenance & Evidence